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USF vs. Vanderbilt prediction: Vanderbilt favored to win women's college basketball matchup [12/15/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get USF vs Vanderbilt predictions for college basketball Monday.
Women's college basketball action continues on Monday at 7:30PM ET as USF takes on Vanderbilt at Memorial Gymnasium.
Based on updated simulations, Dimers' new women's basketball model predicts Vanderbilt as the most likely winner of the USF vs. Vanderbilt game.
This article offers an expanded analysis of Monday's matchup, including best bets and picks.
USF vs. Vanderbilt prediction: Who will win?
Using powerful machine learning and data, we have simulated the outcome of Monday's women's basketball game between USF and Vanderbilt 10,000 times as part of our women's college basketball predictions coverage.
Our leading predictive model currently gives Vanderbilt a 96% chance of defeating South Florida.
According to our model, the 144.5-point over/under has a 52% chance of going over.
USF vs. Vanderbilt odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | USF | Vanderbilt |
|---|---|---|
| Spread | +17.5 (-110) | -17.5 (-110) |
| Moneyline | +1300 | -2381 |
| Total | o144.5 (-110) | u144.5 (-110) |
All odds are correct at the time of publication and are subject to change.
USF vs. Vanderbilt picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Vanderbilt -17.5 | -110 |
| Moneyline | Vanderbilt | -2381 |
| Total | Over 144.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Vanderbilt -17.5 at the spread.
USF vs. Vanderbilt game-day updates and essential details
Monday's women's basketball action between Vanderbilt and USF at Memorial Gymnasium is scheduled to commence at 7:30PM ET.
- Who: South Florida vs. Vanderbilt
- Date: Monday, December 15, 2025
- Time: 7:30PM ET/4:30PM PT
- Venue: Memorial Gymnasium
Conclusion
We predict Vanderbilt, with a 96% win probability, will likely beat South Florida on Monday.
AI and automation have enhanced this article to quickly deliver accurate South Florida vs. Vanderbilt insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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