South Dakota vs. Omaha prediction: Nebraska-Omaha favored to win men's college basketball matchup [1/21/2026]

Omaha will square off with South Dakota in men's college basketball action at Baxter Arena on Wednesday, starting at 8:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Nebraska-Omaha as the most likely winner of the South Dakota vs. Omaha game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

South Dakota vs. Omaha prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between South Dakota and Omaha 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Nebraska-Omaha a 73% chance of beating South Dakota. Our predicted final score has Nebraska-Omaha winning 83-76.

According to our model, the bookmakers have got it right, and South Dakota and Nebraska-Omaha each have a 50% chance of covering the spread, while the 160.5-point over/under also has an equal 50-50 chance of hitting.

South Dakota vs. Omaha odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

South Dakota vs. Omaha picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is South Dakota +6.5 at the spread.

South Dakota vs. Omaha game-day updates and essential details

Wednesday's men's college basketball action between Omaha and South Dakota at Baxter Arena is scheduled to commence at 8:00 PM ET.

• Who: South Dakota vs. Nebraska-Omaha
• Date: Wednesday, January 21, 2026
• Time: 8:00 PM ET/5:00PM PT
• Venue: Baxter Arena

Conclusion

We predict Nebraska-Omaha, with a 73% win probability, will likely beat South Dakota on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate South Dakota vs. Nebraska-Omaha insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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