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South Dakota vs. Missouri prediction: Why Missouri is favored to win men's college basketball matchup [11/20/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get South Dakota vs Missouri predictions for college basketball Thursday.
Missouri and South Dakota will meet in men's college basketball action at Mizzou Arena on Thursday, with tipoff at 8:00PM ET.
Based on updated simulations, Dimers' proven college basketball model predicts Missouri as the most likely winner of the South Dakota vs. Missouri game.
This article offers further insights into Thursday's matchup, including an expanded look at the predicted score, best bets and picks.
South Dakota vs. Missouri prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the result of Thursday's NCAA basketball matchup between South Dakota and Missouri 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives Missouri a 97% chance of beating South Dakota. Our predicted final score has Missouri winning 94-68.
According to our model, the bookies have got it right, and South Dakota and Missouri each have a 50% chance of covering the spread, while the 172.5-point over/under has a 55% chance of staying under.
South Dakota vs. Missouri odds
We have sourced the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | South Dakota | Missouri |
|---|---|---|
| Spread | +25.5 (-108) | -25.5 (-105) |
| Moneyline | +3000 | -5000 |
| Total | o172.5 (-110) | u172.5 (-105) |
All odds are correct at the time of publication and are subject to change.
South Dakota vs. Missouri picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Missouri -25.5 | -105 |
| Moneyline | Missouri | -5000 |
| Total | Under 172.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 172.5 total points.
South Dakota vs. Missouri game-day updates and essential details
Thursday's men's college basketball matchup between Missouri and South Dakota at Mizzou Arena is scheduled to commence at 8:00PM ET.
- Who: South Dakota vs. Missouri
- Date: Thursday, November 20, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: Mizzou Arena
Conclusion
We predict Missouri, with a 97% win probability, will likely beat South Dakota on Thursday.
AI and automation have enhanced this article to quickly deliver accurate South Dakota vs. Missouri insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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