South Dakota State vs. Oregon prediction: Oregon favored to win men's college basketball matchup [11/12/2025]

Oregon will square off with South Dakota State in men's college basketball action at Matthew Knight Arena on Wednesday, beginning at 9:30PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Oregon as the most likely winner of the South Dakota State vs. Oregon game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

South Dakota State vs. Oregon prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's NCAA basketball game between South Dakota State and Oregon 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Oregon a 94% chance of defeating South Dakota State. Our predicted final score has Oregon winning 81-64.

According to our model, Oregon (-16.5) has a 51% chance of covering the spread, while the over/under total of 149.5 points has a 54% chance of going over.

South Dakota State vs. Oregon odds

We have researched the best Men's College Basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

South Dakota State vs. Oregon picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is Over 149.5 total points.

South Dakota State vs. Oregon game-day updates and essential details

Wednesday's men's college basketball matchup between Oregon and South Dakota State at Matthew Knight Arena is scheduled to start at 9:30PM ET.

• Who: South Dakota State vs. Oregon
• Date: Wednesday, November 12, 2025
• Time: 9:30PM ET/6:30PM PT
• Venue: Matthew Knight Arena

Conclusion

We predict Oregon, with a 94% win probability, will likely beat South Dakota State on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate South Dakota State vs. Oregon insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.