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South Carolina State vs. Winthrop prediction: Why Winthrop is favored to win men's college basketball matchup [11/29/2025]

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Written by Dave Garofolo

Get South Carolina State vs Winthrop predictions for college basketball Saturday.

South Carolina State-Winthrop Predictions and Game Preview.
South Carolina State vs. Winthrop men's college basketball prediction for Saturday, November 29, 2025.

Men's college basketball action continues on Saturday at 4:00PM ET as South Carolina State looks to defy the odds against Winthrop in men's college basketball action at Winthrop Coliseum.

Based on updated simulations, Dimers' proven college basketball model predicts Winthrop as the most likely winner of the South Carolina State vs. Winthrop game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

South Carolina State vs. Winthrop prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between South Carolina State and Winthrop 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Winthrop a 95% chance of defeating South Carolina State. Our predicted final score has Winthrop winning 90-70.

According to our model, the bookmakers have got it right, and South Carolina State and Winthrop each have a 50% chance of covering the spread, while the 161.5-point over/under has a 53% chance of going over.

 

South Carolina State vs. Winthrop odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type South Carolina State Winthrop
Spread +19.5 (-102) -19.5 (-118)
Moneyline +1800 -3000
Total o161.5 (-106) u161.5 (-114)

All odds are correct at the time of publication and are subject to change.

South Carolina State vs. Winthrop picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread South Carolina State +19.5 -102
Moneyline South Carolina State +1800
Total Over 161.5 -106

According to our men's college basketball best bets, the top play to make on this game is Over 161.5 total points.

 

South Carolina State vs. Winthrop game-day updates and essential details

Saturday's men's college basketball game between Winthrop and South Carolina State at Winthrop Coliseum is scheduled to start at 4:00PM ET.

  • Who: South Carolina State vs. Winthrop
  • Date: Saturday, November 29, 2025
  • Time: 4:00PM ET/1:00PM PT
  • Venue: Winthrop Coliseum

 

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Conclusion

We predict Winthrop, with a 95% win probability, will likely beat South Carolina State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate South Carolina State vs. Winthrop insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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