South Carolina State vs. Charleston Southern prediction: Why Charleston Southern is favored to win men's college basketball matchup [12/8/2025]

Charleston Southern will face South Carolina State in men's college basketball action at The Buc Dome on Monday, commencing at 7:00PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Charleston Southern as the most likely winner of the South Carolina State vs. Charleston Southern game.

This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and picks.

South Carolina State vs. Charleston Southern prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Monday's NCAA basketball matchup between South Carolina State and Charleston Southern 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Charleston Southern an 84% chance of defeating South Carolina State. Our predicted final score has Charleston Southern winning 81-70.

According to our model, Charleston Southern (-10.5) has a 51% chance of covering the spread, while the over/under total of 152.5 points has a 52% chance of staying under.

South Carolina State vs. Charleston Southern odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

South Carolina State vs. Charleston Southern picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: