SMU vs. Louisville prediction: Louisville favored to win women's college basketball matchup [1/1/2026]

Louisville and SMU will meet in the women's college basketball at KFC Yum! Center on New Year's Day, with tipoff at 2:00 PM ET.

Based on the latest simulation results, Dimers' new women's basketball model predicts Louisville as the most likely winner of the SMU vs. Louisville game.

This article offers a closer look at Thursday's matchup, including best bets and picks.

SMU vs. Louisville prediction: Who will win?

Using trusted machine learning and data analysis, we have simulated the result of Thursday's women's basketball matchup between SMU and Louisville 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model gives Louisville a 99% chance of beating SMU.

According to our model, the 141.5-point over/under has a 59% chance of staying under.

SMU vs. Louisville odds

We have researched the best women's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

SMU vs. Louisville picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: