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SMU vs. Louisville prediction: Louisville favored to win women's college basketball matchup [1/1/2026]

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Written by Ryan Leaver

Get SMU vs Louisville predictions for college basketball Thursday.

SMU-Louisville Predictions and Game Preview.
SMU vs. Louisville women's college basketball prediction for Thursday, January 1, 2026.

Louisville will square off with SMU in women's college basketball action at KFC Yum! Center on New Year's Day, starting at 2:00 PM ET.

Based on the latest simulations, Dimers' new women's basketball model projects Louisville as the most likely winner of the SMU vs. Louisville game.

This article offers further insights into Thursday's matchup, including best bets and picks.

SMU vs. Louisville prediction: Who will win?

Using powerful machine learning and data, we have simulated the result of Thursday's women's basketball game between SMU and Louisville 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model currently gives Louisville a 99% chance of beating SMU.

According to our model, the over/under total of 141.5 points has a 59% chance of staying under.

 

SMU vs. Louisville odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type SMU Louisville
Spread +32.5 (-110) -32.5 (-110)
Total o141.5 (-110) u141.5 (-110)

All odds are correct at the time of publication and are subject to change.

SMU vs. Louisville picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread SMU +32.5 -110
Total Under 141.5 -110

According to our women's college basketball best bets, the top play to make on this game is SMU +32.5.

 

SMU vs. Louisville game-day updates and essential details

Thursday's women's basketball matchup between Louisville and SMU at KFC Yum! Center is scheduled to start at 2:00 PM ET.

  • Who: SMU vs. Louisville
  • Date: Thursday, January 1, 2026
  • Time: 2:00 PM ET/11:00AM PT
  • Venue: KFC Yum! Center

Conclusion

We predict Louisville, with a 99% win probability, will likely beat SMU on New Year's Day.

AI and automation have enhanced this article to quickly deliver accurate SMU vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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