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SMU vs. Louisville prediction: Louisville favored to win men's college basketball matchup [1/31/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get SMU vs Louisville predictions for college basketball Saturday.
Louisville will face SMU in men's college basketball action at KFC Yum! Center on Saturday, beginning at 2:00 PM ET.
Based on updated simulations, Dimers' proven college basketball model predicts Louisville as the most likely winner of the SMU vs. Louisville game.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
SMU vs. Louisville prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball game between SMU and Louisville 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Louisville an 84% chance of defeating SMU. Our predicted final score has Louisville winning 85-74.
According to our model, Louisville (-9.5) has a 54% chance of covering the spread, while the over/under total of 161.5 points has a 51% chance of staying under.
SMU vs. Louisville odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | SMU | Louisville |
|---|---|---|
| Spread | +9.5 (-102) | -9.5 (-115) |
| Moneyline | +420 | -500 |
| Total | o161.5 (-110) | u161.5 (-110) |
All odds are correct at the time of publication and are subject to change.
SMU vs. Louisville picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Louisville -9.5 | -115 |
| Moneyline | Louisville | -500 |
| Total | Under 161.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Louisville to win.
SMU vs. Louisville game-day updates and essential details
Saturday's men's college basketball game between Louisville and SMU at KFC Yum! Center is scheduled to start at 2:00 PM ET.
- Who: SMU vs. Louisville
- Date: Saturday, January 31, 2026
- Time: 2:00 PM ET/11:00AM PT
- Venue: KFC Yum! Center
Conclusion
We predict Louisville, with an 84% win probability, will likely beat SMU on Saturday.
AI and automation have enhanced this article to quickly deliver accurate SMU vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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