SMU vs. Duke prediction: Duke favored to win men's college basketball matchup [1/10/2026]

Men's college basketball action continues on Saturday at 2:00 PM ET as SMU takes on Duke in men's college basketball action at Cameron Indoor Stadium.

Based on updated simulation results, Dimers' proven college basketball model predicts Duke as the most likely winner of the SMU vs. Duke game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

SMU vs. Duke prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball game between SMU and Duke 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Duke a 92% chance of beating SMU. Our predicted final score has Duke winning 85-69.

According to our model, Duke (-16.5) has a 53% chance of covering the spread, while the 154.5-point over/under has a 56% chance of staying under.

SMU vs. Duke odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

SMU vs. Duke picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: