SIUE vs. Southeast Missouri State prediction: Southeast Missouri State favored to win men's college basketball matchup [1/17/2026]

Men's college basketball action continues on Saturday at 4:45 PM ET as SIUE squares off with Southeast Missouri State in men's college basketball action at Show Me Center.

Based on updated simulation results, Dimers' proven college basketball model predicts Southeast Missouri State as the most likely winner of the SIUE vs. Southeast Missouri State game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

SIUE vs. Southeast Missouri State prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Saturday's NCAA basketball game between SIUE and Southeast Missouri State 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Southeast Missouri State a 77% chance of beating SIU-Edwardsville. Our predicted final score has Southeast Missouri State winning 73-66.

According to our model, the bookmakers have got it right, and SIU-Edwardsville and Southeast Missouri State each have a 50% chance of covering the spread, while the 140.5-point over/under has a 53% chance of staying under.

SIUE vs. Southeast Missouri State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

SIUE vs. Southeast Missouri State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: