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Siena vs. American University prediction: Why Siena is favored to win men's college basketball matchup [11/29/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Siena vs American University predictions for college basketball Saturday.
American University and Siena will meet in men's college basketball action at Bender Arena on Saturday, with tipoff at 4:00PM ET.
Based on updated simulations, Dimers' proven college basketball model predicts Siena as the most likely winner of the Siena vs. American University game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Siena vs. American University prediction: Who will win and cover?
Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball game between Siena and American University 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Siena a 56% chance of defeating American University. Our predicted final score has Siena winning 70-69.
According to our model, American University (+1.5) has a 56% chance of covering the spread, while the over/under total of 137.5 points has a 53% chance of going over.
Siena vs. American University odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Siena | American University |
|---|---|---|
| Spread | -1.5 (-115) | +1.5 (-102) |
| Moneyline | -135 | +116 |
| Total | o137.5 (-108) | u137.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Siena vs. American University picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | American University +1.5 | -102 |
| Moneyline | Siena | -135 |
| Total | Over 137.5 | -108 |
According to our men's college basketball best bets, the top play to make on this game is American University +1.5 at the spread.
Siena vs. American University game-day updates and essential details
Saturday's men's college basketball game between American University and Siena at Bender Arena is scheduled to start at 4:00PM ET.
- Who: Siena vs. American University
- Date: Saturday, November 29, 2025
- Time: 4:00PM ET/1:00PM PT
- Venue: Bender Arena
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Conclusion
We predict Siena, with a 56% win probability, will likely beat American University on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Siena vs. American University insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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