Seton Hall vs. St. John's prediction: St. John's favored to win men's college basketball matchup [1/20/2026]

St. John's will take on Seton Hall in men's college basketball action at Madison Square Garden on Tuesday, commencing at 7:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts St. John's as the most likely winner of the Seton Hall vs. St. John's game.

This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Seton Hall vs. St. John's prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Tuesday's NCAA basketball game between Seton Hall and St. John's 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives St. John's an 86% chance of defeating Seton Hall. Our predicted final score has St. John's winning 81-69.

According to our model, St. John's (-10.5) has a 56% chance of covering the spread, while the over/under total of 145.5 points has a 56% chance of going over.

Seton Hall vs. St. John's odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Seton Hall vs. St. John's picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: