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Seton Hall vs. DePaul prediction: Seton Hall favored to win men's college basketball matchup [1/24/2026]

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Written by Dave Garofolo

Get Seton Hall vs DePaul predictions for college basketball Saturday.

Seton Hall-DePaul Predictions and Game Preview.
Seton Hall vs. DePaul men's college basketball prediction for Saturday, January 24, 2026.

DePaul will take on Seton Hall in men's college basketball action at Wintrust Arena on Saturday, commencing at 5:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Seton Hall as the most likely winner of the Seton Hall vs. DePaul game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Seton Hall vs. DePaul prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Saturday's NCAA basketball game between Seton Hall and DePaul 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Seton Hall a 57% chance of beating DePaul. Our predicted final score has Seton Hall winning 69-67.

According to our model, Seton Hall (+2.5) has a 57% chance of covering the spread, while the over/under total of 134.5 points has a 54% chance of going over.

 

Seton Hall vs. DePaul odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Seton Hall DePaul
Spread +2.5 (-110) -2.5 (-114)
Moneyline +130 -162
Total o134.5 (-110) u134.5 (-120)

All odds are correct at the time of publication and are subject to change.

Seton Hall vs. DePaul picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Seton Hall +2.5 -110
Moneyline Seton Hall +130
Total Over 134.5 -110

According to our men's college basketball best bets, the top play to make on this game is Seton Hall to win.

 

Seton Hall vs. DePaul game-day updates and essential details

Saturday's men's college basketball matchup between DePaul and Seton Hall at Wintrust Arena is scheduled to commence at 5:00 PM ET.

  • Who: Seton Hall vs. DePaul
  • Date: Saturday, January 24, 2026
  • Time: 5:00 PM ET/2:00PM PT
  • Venue: Wintrust Arena

Conclusion

We predict Seton Hall, with a 57% win probability, will likely beat DePaul on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Seton Hall vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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