Seattle vs. Santa Clara prediction: Santa Clara favored to win men's college basketball matchup [2/11/2026]

Santa Clara and Seattle are scheduled to meet in men's college basketball action at Leavey Center on Wednesday, starting at 10:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Santa Clara as the most likely winner of the Seattle vs. Santa Clara game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Seattle vs. Santa Clara prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between Seattle and Santa Clara 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Santa Clara an 89% chance of defeating Seattle. Our predicted final score has Santa Clara winning 80-67.

According to our model, Santa Clara (-12.5) has a 54% chance of covering the spread, while the 147.5-point over/under has a 51% chance of going over.

Seattle vs. Santa Clara odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Seattle vs. Santa Clara picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Santa Clara -12.5 at the spread.

Seattle vs. Santa Clara game-day updates and essential details

Wednesday's men's college basketball action between Santa Clara and Seattle at Leavey Center is scheduled to start at 10:00 PM ET.

• Who: Seattle vs. Santa Clara
• Date: Wednesday, February 11, 2026
• Time: 10:00 PM ET/7:00PM PT
• Venue: Leavey Center

Conclusion

We predict Santa Clara, with an 89% win probability, will likely beat Seattle on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Seattle vs. Santa Clara insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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