Santa Clara vs. San Diego prediction: Santa Clara favored to win men's college basketball matchup [1/24/2026]

Men's college basketball action continues on Saturday at 9:30 PM ET as the favored Santa Clara takes on San Diego in men's college basketball action at Jenny Craig Pavilion.

Based on updated simulation results, Dimers' proven college basketball model projects Santa Clara as the most likely winner of the Santa Clara vs. San Diego game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Santa Clara vs. San Diego prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball game between Santa Clara and San Diego 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Santa Clara an 87% chance of defeating San Diego. Our predicted final score has Santa Clara winning 82-70.

According to our model, San Diego (+13.5) has a 53% chance of covering the spread, while the over/under total of 162.5 points has a 58% chance of staying under.

Santa Clara vs. San Diego odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Santa Clara vs. San Diego picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is Under 162.5 total points.

Santa Clara vs. San Diego game-day updates and essential details

Saturday's men's college basketball action between San Diego and Santa Clara at Jenny Craig Pavilion is scheduled to start at 9:30 PM ET.

• Who: Santa Clara vs. San Diego
• Date: Saturday, January 24, 2026
• Time: 9:30 PM ET/6:30PM PT
• Venue: Jenny Craig Pavilion

Conclusion

We predict Santa Clara, with an 87% win probability, will likely beat San Diego on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Santa Clara vs. San Diego insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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