San Francisco vs. Pepperdine prediction: Why San Francisco is favored to win men's college basketball matchup [1/10/2026]

Pepperdine will square off with the favored San Francisco in men's college basketball action at Firestone Fieldhouse on Saturday, beginning at 8:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts San Francisco as the most likely winner of the San Francisco vs. Pepperdine game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

San Francisco vs. Pepperdine prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between San Francisco and Pepperdine 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives San Francisco an 84% chance of defeating Pepperdine. Our predicted final score has San Francisco winning 74-64.

According to our model, San Francisco (-7.5) has a 60% chance of covering the spread, while the 140.5-point over/under has an equal 50-50 chance of hitting.

San Francisco vs. Pepperdine odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

San Francisco vs. Pepperdine picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: