San Francisco vs. Mississippi State prediction: Why Mississippi State is favored to win men's college basketball matchup [12/7/2025]

Mississippi State will face San Francisco in men's college basketball action at Cadence Bank Arena on Sunday, starting at 4:00PM ET.

Based on the latest simulations, Dimers' advanced college basketball model projects Mississippi State as the most likely winner of the San Francisco vs. Mississippi State game.

This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

San Francisco vs. Mississippi State prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Sunday's NCAA basketball matchup between San Francisco and Mississippi State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Mississippi State a 63% chance of defeating San Francisco. Our predicted final score has Mississippi State winning 78-75.

According to our model, San Francisco (+4.5) has a 55% chance of covering the spread, while the 150.5-point over/under has a 54% chance of going over.

San Francisco vs. Mississippi State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

San Francisco vs. Mississippi State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: