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San Francisco vs. Mississippi State prediction: Why Mississippi State is favored to win men's college basketball matchup [12/7/2025]
Get San Francisco vs Mississippi State predictions for college basketball Sunday.

Mississippi State will take on San Francisco in men's college basketball action at Cadence Bank Arena on Sunday, commencing at 4:00PM ET.
Based on the latest simulations, Dimers' advanced college basketball model predicts Mississippi State as the most likely winner of the San Francisco vs. Mississippi State game.
This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
San Francisco vs. Mississippi State prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Sunday's NCAA basketball matchup between San Francisco and Mississippi State 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Mississippi State a 63% chance of defeating San Francisco. Our predicted final score has Mississippi State winning 78-75.
According to our model, San Francisco (+4.5) has a 55% chance of covering the spread, while the 150.5-point over/under has a 54% chance of going over.
San Francisco vs. Mississippi State odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | San Francisco | Mississippi State |
|---|---|---|
| Spread | +4.5 (-110) | -4.5 (-105) |
| Moneyline | +172 | -192 |
| Total | o150.5 (-115) | u150.5 (-105) |
All odds are correct at the time of publication and are subject to change.
San Francisco vs. Mississippi State picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | San Francisco +4.5 | -110 |
| Moneyline | San Francisco | +172 |
| Total | Over 150.5 | -115 |
According to our best men's college basketball bets, the top play to make on this game is San Francisco +4.5 at the spread.
San Francisco vs. Mississippi State game-day updates and essential details
Sunday's men's college basketball game between Mississippi State and San Francisco at Cadence Bank Arena is scheduled to begin at 4:00PM ET.
- Who: San Francisco vs. Mississippi State
- Date: Sunday, December 7, 2025
- Time: 4:00PM ET/1:00PM PT
- Venue: Cadence Bank Arena
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Conclusion
We predict Mississippi State, with a 63% win probability, will likely beat San Francisco on Sunday.
AI and automation have enhanced this article to quickly deliver accurate San Francisco vs. Mississippi State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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