Giants vs. Twins Prediction: Minnesota Predicted to Win Friday's MLB Matchup [5/9/2025]

The Minnesota Twins will face the San Francisco Giants in MLB action at Target Field on Friday, starting at 8:10PM ET.

Chris Paddack (0-3, 5.57 ERA) will get the ball for the Twins, pitting him against Jordan Hicks (1-3, 6.03 ERA) for the Giants.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Twins as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's San Francisco-Minnesota game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Twins' chance of winning is 51%, while the Giants' is 49%."

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Giants vs. Twins predictions page.

Twins vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and statistical analysis, we have simulated the result of Friday's MLB matchup between the Giants and Twins 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Twins a 51% chance of beating the Giants.

According to our model, the Twins (+1.5) have a 63% chance of covering the run line, while the 9-run over/under has a 54% chance of staying under.

Giants vs. Twins Odds [5/9/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Giants	Twins
Run Line	-1.5 (+142)	+1.5 (-166)
Moneyline	-112	-102
Total	o9 (-105)	u9 (-115)

All odds are correct at the time of publication and are subject to change.

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Giants vs. Twins Picks and Best Bets

Our model's biggest edge in today's Giants vs. Twins matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Giants vs. Twins Game-Day Updates and Essential Details

Friday's MLB game between the Twins and Giants at Target Field is scheduled to begin at 8:10PM ET.

• Who: San Francisco Giants vs. Minnesota Twins
• Date: Friday, May 9, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Target Field

Dimers.com's full preview of Friday's Giants vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any San Francisco vs. Minnesota picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
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Conclusion

We predict the Twins, with a 51% win probability, will likely beat the Giants on Friday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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