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San Diego vs. Santa Clara prediction: Santa Clara favored to win men's college basketball matchup [1/4/2026]

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Written by Jason Bevilacqua

Get San Diego vs Santa Clara predictions for college basketball Sunday.

San Diego-Santa Clara Predictions and Game Preview.
San Diego vs. Santa Clara men's college basketball prediction for Sunday, January 4, 2026.

Men's college basketball action continues on Sunday at 7:00 PM ET as San Diego takes on the favored Santa Clara in men's college basketball action at Leavey Center.

Based on updated simulation results, Dimers' proven college basketball model projects Santa Clara as the most likely winner of the San Diego vs. Santa Clara game.

This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

San Diego vs. Santa Clara prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Sunday's NCAA basketball game between San Diego and Santa Clara 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Santa Clara a 94% chance of defeating San Diego. Our predicted final score has Santa Clara winning 87-69.

According to our model, the bookies have got it right, and San Diego and Santa Clara each have a 50% chance of covering the spread, while the over/under total of 161.5 points has a 54% chance of staying under.

 

San Diego vs. Santa Clara odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type San Diego Santa Clara
Spread +17.5 (-110) -17.5 (-106)
Moneyline +1100 -1650
Total o161.5 (-106) u161.5 (-105)

All odds are correct at the time of publication and are subject to change.

San Diego vs. Santa Clara picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Santa Clara -17.5 -106
Moneyline Santa Clara -1650
Total Under 161.5 -105

According to our men's college basketball best bets, the top play to make on this game is Under 161.5 total points.

 

San Diego vs. Santa Clara game-day updates and essential details

Sunday's men's college basketball matchup between Santa Clara and San Diego at Leavey Center is scheduled to commence at 7:00 PM ET.

  • Who: San Diego vs. Santa Clara
  • Date: Sunday, January 4, 2026
  • Time: 7:00 PM ET/4:00PM PT
  • Venue: Leavey Center

Conclusion

We predict Santa Clara, with a 94% win probability, will likely beat San Diego on Sunday.

AI and automation have enhanced this article to quickly deliver accurate San Diego vs. Santa Clara insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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