San Diego vs. Pepperdine prediction: Why San Diego is favored to win men's college basketball matchup [1/28/2026]

Pepperdine will take on San Diego in men's college basketball action at Firestone Fieldhouse on Wednesday, starting at 9:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model projects San Diego as the most likely winner of the San Diego vs. Pepperdine game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

San Diego vs. Pepperdine prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Wednesday's NCAA basketball matchup between San Diego and Pepperdine 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives San Diego a 62% chance of beating Pepperdine. Our predicted final score has San Diego winning 77-73.

According to our model, San Diego (-2.5) has a 56% chance of covering the spread, while the over/under total of 151.5 points has a 52% chance of staying under.

San Diego vs. Pepperdine odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

San Diego vs. Pepperdine picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is San Diego -2.5 at the spread.

San Diego vs. Pepperdine game-day updates and essential details

Wednesday's men's college basketball action between Pepperdine and San Diego at Firestone Fieldhouse is scheduled to start at 9:00 PM ET.

• Who: San Diego vs. Pepperdine
• Date: Wednesday, January 28, 2026
• Time: 9:00 PM ET/6:00PM PT
• Venue: Firestone Fieldhouse

Conclusion

We predict San Diego, with a 62% win probability, will likely beat Pepperdine on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate San Diego vs. Pepperdine insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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