Padres vs. Rockies Prediction: San Diego Predicted to Win Saturday's MLB Matchup [5/10/2025]

The Colorado Rockies will face the favored San Diego Padres in MLB action at Coors Field on Saturday, starting at 8:10PM ET.

Bradley Blalock (0-1, 8.03 ERA) will be on the bump for the Rockies, while the Padres will counter with Stephen Kolek (1-0, 0.00 ERA).

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Padres as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's San Diego-Colorado game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Padres are more likely to win, while the Rockies have a lower chance of victory."

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Padres vs. Rockies predictions page.

Rockies vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Saturday's MLB matchup between the Padres and Rockies 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Padres a 67% chance of beating the Rockies.

According to our model, the Padres (-1.5) have a 57% chance of covering the run line, while the 12-run over/under has a 55% chance of staying under.

Padres vs. Rockies Odds [5/10/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Rockies
Run Line	-1.5 (-166)	+1.5 (+142)
Moneyline	-240	+205
Total	o12 (-110)	u12 (-108)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Rockies Picks and Best Bets

Our model's biggest edge in today's Padres vs. Rockies matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

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Padres vs. Rockies Game-Day Updates and Essential Details

Saturday's MLB game between the Rockies and Padres at Coors Field is scheduled to commence at 8:10PM ET.

• Who: San Diego Padres vs. Colorado Rockies
• Date: Saturday, May 10, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Coors Field

Dimers.com's full preview of Saturday's Padres vs. Rockies matchup includes our prediction, picks and the latest betting odds.

Before making any San Diego vs. Colorado picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Padres, with a 67% win probability, will likely beat the Rockies on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Rockies insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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