Jul 19, 2025
Brewers vs. Dodgers Prediction: Dodgers Predicted to Win Saturday's MLB Matchup [7/19/2025]
Read Article Padres vs. Reds Prediction: Cincinnati Predicted to Win Saturday's MLB Matchup [6/28/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Our expert prediction for Saturday's San Diego Padres vs Cincinnati Reds matchup.
The Cincinnati Reds will square off with the San Diego Padres in MLB action at Great American Ball Park on Saturday, commencing at 4:10PM ET.
Andrew Abbott (7-1, 1.79 ERA) will start for the Reds, pitting him against Randy Vásquez (3-4, 3.60 ERA) for the Padres.
Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.
"Our team has used the latest data to run 10,000 simulations of Saturday's Padres-Reds game," said Dimers' Chief Content Officer, Nick Slade.
"By incorporating recent updates and various other inputs, we estimate that the Reds are more likely to win, while the Padres have a lower chance of victory."
For further insights into Saturday's matchup, including best bets and picks, visit our interactive Padres vs. Reds predictions page.
Get 20% off Dimers Pro With Code 20BASEBALL Get Dimers Pro Reds vs. Padres Prediction: Who Will Win, Cover the Run Line?
Using powerful machine learning and data, we have simulated the outcome of Saturday's MLB game between the Padres and Reds 10,000 times as part of our MLB predictions coverage.
Our leading predictive model currently gives the Reds a 56% chance of defeating the Padres.
According to our model, the Padres (+1.5) have a 61% chance of covering the run line, while the over/under total of 9.5 runs has a 55% chance of staying under.
Pre-Game Probabilities
Last Updated: 8:30PM, Jun 28
Moneyline
Over / Under
Run Line
Randy Vásquez 3-4, 3.60 ERA
Andrew Abbott 7-1, 1.79 ERA
Get the best bets with Dimers Pro
Padres vs. Reds Odds [6/28/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Padres | Reds |
|---|---|---|
| Run Line | +1.5 (-145) | -1.5 (+133) |
| Moneyline | +132 | -151 |
| Total | o9.5 (-105) | u9.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Padres vs. Reds Picks and Best Bets
Our model's biggest edge in today's Padres vs. Reds matchup is on the run line.
Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.
Unlock Every Padres-Reds Pick Get Dimers Pro Calling Our Shot's Best Bets Video
Calling Our Shot produces daily MLB betting content, including the predictions featured below.
Padres vs. Reds Game-Day Updates and Essential Details
Saturday's MLB action between the Reds and Padres at Great American Ball Park is scheduled to start at 4:10PM ET.
- Who: San Diego Padres vs. Cincinnati Reds
- Date: Saturday, June 28, 2025
- Time: 4:10PM ET/1:10PM PT
- Venue: Great American Ball Park
Dimers.com's full preview of Saturday's Padres vs. Reds matchup includes our prediction, picks and the latest betting odds.
Before making any Padres vs. Reds picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Key MLB Betting Guides and Insights
- Explore how MLB odds work and dive into MLB live betting strategies
- Understand where sports odds come from and how they're applied to baseball matchups
- Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
- Stay informed with where online sports betting is currently legal and which betting sites are safest to use
- Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on
Conclusion
We predict the Reds, with a 56% win probability, will likely beat the Padres on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Padres vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
More on MLB
Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
Advertiser disclosure
Swipe across to view more offers 
