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Spurs vs. Pelicans prediction: San Antonio favored to win Friday's NBA matchup [10/24/2025]

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Written by Jason Bevilacqua

Get San Antonio Spurs vs New Orleans Pelicans predictions for NBA Friday.

San Antonio Spurs-New Orleans Pelicans Predictions and Game Preview.
San Antonio Spurs vs. New Orleans Pelicans NBA prediction for Friday, October 24, 2025.

The New Orleans Pelicans and San Antonio Spurs will lock horns in NBA action at Smoothie King Center on Friday, starting at 8:00PM ET.

Based on updated simulation results and today’s injury news, Dimers' proven NBA model predicts the Spurs as the most likely winner of the Spurs vs. Pelicans game.

This prediction follows the latest NBA Injury Report, which suggests the Pelicans lineup will feature players like Zion Williamson, Trey Murphy and Jordan Poole, while the Spurs will rely on Victor Wembanyama, Stephon Castle and Devin Vassell.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Spurs vs. Pelicans prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the outcome of Friday's NBA matchup between the Spurs and Pelicans 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Spurs a 65% chance of defeating the Pelicans. Our predicted final score has the Spurs winning 118-114.

According to our model, the Spurs (-3.5) have a 51% chance of covering the spread, while the 233.5-point over/under has a 52% chance of staying under.

 

Spurs vs. Pelicans odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Spurs Pelicans
Spread -3.5 (-115) +3.5 (-105)
Moneyline -172 +145
Total o233.5 (-108) u233.5 (-105)

All odds are correct at the time of publication and are subject to change.

Spurs vs. Pelicans picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Pelicans +3.5 -105
Moneyline Spurs -172
Total Under 233.5 -105

According to our NBA best bets, the top play to make on this game is Spurs moneyline.

 

Spurs vs. Pelicans player props

NBA prop bets are a great way to wager on Friday's San Antonio vs. New Orleans matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Smoothie King Center.

Victor Wembanyama is expected to lead the Spurs with 27 points, 12 rebounds and 4 assists, while Zion Williamson is projected to have 28 points, 8 rebounds and 7 assists for the Pelicans.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Spurs prediction

Our model's projected player stats for the Spurs are:

Player PTS REB AST 3PM
Victor Wembanyama 27 12 4 3
Stephon Castle 19 5 6 2
Devin Vassell 17 4 3 3
Keldon Johnson 14 5 2 2
Harrison Barnes 14 4 2 3

Pelicans prediction

Projected points, rebounds, assists and three-pointers made for the Pelicans:

Player PTS REB AST 3PM
Zion Williamson 28 8 7 0
Trey Murphy 21 5 4 3
Jordan Poole 19 3 5 3
Saddiq Bey 13 6 2 2
Herbert Jones 11 4 3 2

Spurs vs. Pelicans game-day updates and essential details

Friday's action between the Pelicans and Spurs at Smoothie King Center is scheduled to begin at 8:00PM ET.

Conclusion

We predict the Spurs, with a 65% win probability, will likely beat the Pelicans on Friday.

AI and automation have enhanced this article to quickly deliver accurate Spurs vs. Pelicans insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NBA

Keep up with the latest NBA news and NBA parlay picks throughout the season. Plus, our NBA championship odds offer the most up-to-date probabilities for the NBA title.

Boost your NBA betting by exploring the latest NBA betting promos, sourced from top sportsbooks and DFS operators.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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