Saint Mary's vs. Santa Clara prediction: Santa Clara favored to win men's college basketball matchup [1/17/2026]

Santa Clara and Saint Mary's will lock horns in men's college basketball action at Leavey Center on Saturday, starting at 7:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model projects Santa Clara as the most likely winner of the Saint Mary's vs. Santa Clara game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Saint Mary's vs. Santa Clara prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball matchup between Saint Mary's and Santa Clara 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Santa Clara a 56% chance of defeating Saint Mary's. Our predicted final score has Santa Clara winning 78-77.

According to our model, Saint Mary's (+1.5) has a 52% chance of covering the spread, while the over/under total of 155.5 points has a 51% chance of staying under.

Saint Mary's vs. Santa Clara odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Saint Mary's vs. Santa Clara picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: