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Saint Louis vs. Duquesne prediction: Saint Louis favored to win men's college basketball matchup [1/20/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Saint Louis vs Duquesne predictions for college basketball Tuesday.
Duquesne and Saint Louis are scheduled to meet in men's college basketball action at UPMC Cooper Fieldhouse on Tuesday, starting at 7:00 PM ET.
Based on updated simulations, Dimers' advanced college basketball model projects Saint Louis as the most likely winner of the Saint Louis vs. Duquesne game.
This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Saint Louis vs. Duquesne prediction: Who will win and cover?
Using trusted machine learning and data analysis, we have simulated the result of Tuesday's NCAA basketball matchup between Saint Louis and Duquesne 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives Saint Louis a 75% chance of defeating Duquesne. Our predicted final score has Saint Louis winning 84-76.
According to our model, Duquesne (+9.5) has a 57% chance of covering the spread, while the over/under total of 164.5 points has a 54% chance of staying under.
Saint Louis vs. Duquesne odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Saint Louis | Duquesne |
|---|---|---|
| Spread | -9.5 (-102) | +9.5 (-120) |
| Moneyline | -425 | +350 |
| Total | o164.5 (-115) | u164.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Saint Louis vs. Duquesne picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Duquesne +9.5 | -120 |
| Moneyline | Duquesne | +350 |
| Total | Under 164.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Duquesne to win.
Saint Louis vs. Duquesne game-day updates and essential details
Tuesday's men's college basketball game between Duquesne and Saint Louis at UPMC Cooper Fieldhouse is scheduled to begin at 7:00 PM ET.
- Who: Saint Louis vs. Duquesne
- Date: Tuesday, January 20, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: UPMC Cooper Fieldhouse
Conclusion
We predict Saint Louis, with a 75% win probability, will likely beat Duquesne on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Saint Louis vs. Duquesne insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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