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Saint Joseph's (PA) vs. Loyola Chicago prediction: Saint Joseph's (PA) favored to win men's college basketball matchup [1/27/2026]
Get Saint Joseph's (PA) vs Loyola Chicago predictions for college basketball Tuesday.

Loyola Chicago will face Saint Joseph's (PA) in men's college basketball action at Joseph J. Gentile Arena on Tuesday, beginning at 9:00 PM ET.
Based on the latest simulations, Dimers' proven college basketball model predicts Saint Joseph's (PA) as the most likely winner of the Saint Joseph's (PA) vs. Loyola Chicago game.
This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Saint Joseph's (PA) vs. Loyola Chicago prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Tuesday's NCAA basketball game between Saint Joseph's (PA) and Loyola Chicago 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Saint Joseph's (PA) a 59% chance of defeating Loyola Chicago. Our predicted final score has Saint Joseph's (PA) winning 72-70.
According to our model, Loyola Chicago (+1.5) has a 51% chance of covering the spread, while the over/under total of 143.5 points has a 52% chance of staying under.
Saint Joseph's (PA) vs. Loyola Chicago odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Saint Joseph's (PA) | Loyola Chicago |
|---|---|---|
| Spread | -1.5 (-115) | +1.5 (-105) |
| Moneyline | -135 | +122 |
| Total | o143.5 (-115) | u143.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Saint Joseph's (PA) vs. Loyola Chicago picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Loyola Chicago +1.5 | -105 |
| Moneyline | Saint Joseph's (PA) | -135 |
| Total | Under 143.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Saint Joseph's (PA) to win.
Saint Joseph's (PA) vs. Loyola Chicago game-day updates and essential details
Tuesday's men's college basketball matchup between Loyola Chicago and Saint Joseph's (PA) at Joseph J. Gentile Arena is scheduled to commence at 9:00 PM ET.
- Who: Saint Joseph's (PA) vs. Loyola Chicago
- Date: Tuesday, January 27, 2026
- Time: 9:00 PM ET/6:00PM PT
- Venue: Joseph J. Gentile Arena
Conclusion
We predict Saint Joseph's (PA), with a 59% win probability, will likely beat Loyola Chicago on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Saint Joseph's (PA) vs. Loyola Chicago insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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