Sacred Heart vs. Siena prediction: Siena favored to win men's college basketball matchup [1/14/2026]

Siena will square off with Sacred Heart in men's college basketball action at MVP Arena on Wednesday, starting at 7:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Siena as the most likely winner of the Sacred Heart vs. Siena game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Sacred Heart vs. Siena prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between Sacred Heart and Siena 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Siena an 80% chance of defeating Sacred Heart. Our predicted final score has Siena winning 74-66.

According to our model, the bookmakers have got it right, and Sacred Heart and Siena each have a 50% chance of covering the spread, while the 138.5-point over/under has a 54% chance of staying under.

Sacred Heart vs. Siena odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Sacred Heart vs. Siena picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: