Purdue Fort Wayne vs. Northern Kentucky prediction: Northern Kentucky favored to win men's college basketball matchup [2/18/2026]

Men's college basketball action continues on Wednesday at 7:00 PM ET as Purdue Fort Wayne faces off with the favored Northern Kentucky in men's college basketball action at Truist Arena.

Based on updated simulations, Dimers' advanced college basketball model predicts Northern Kentucky as the most likely winner of the Purdue Fort Wayne vs. Northern Kentucky game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Purdue Fort Wayne vs. Northern Kentucky prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Wednesday's NCAA basketball matchup between Purdue Fort Wayne and Northern Kentucky 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Northern Kentucky a 67% chance of defeating Purdue Fort Wayne. Our predicted final score has Northern Kentucky winning 78-73.

According to our model, Purdue Fort Wayne (+5.5) has a 55% chance of covering the spread, while the over/under total of 153.5 points has a 52% chance of staying under.

Purdue Fort Wayne vs. Northern Kentucky odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Purdue Fort Wayne vs. Northern Kentucky picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: