Pittsburgh vs. Notre Dame prediction: Notre Dame favored to win women's college basketball matchup [12/29/2025]

Women's college basketball action continues on Monday at 6:00 PM ET as Pittsburgh squares off with Notre Dame at Purcell Pavilion.

Based on updated simulation results, Dimers' new women's basketball model projects Notre Dame as the most likely winner of the Pittsburgh vs. Notre Dame game.

This article offers further insights into Monday's matchup, including best bets and picks.

Pittsburgh vs. Notre Dame prediction: Who will win?

Using innovative machine learning and data analysis, we have simulated the result of Monday's women's basketball matchup between Pittsburgh and Notre Dame 10,000 times as part of our women's college basketball predictions coverage.

Our famous predictive model gives Notre Dame a 99% chance of defeating Pittsburgh.

According to our model, the 138.5-point over/under has a 55% chance of staying under.

Pittsburgh vs. Notre Dame odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Pittsburgh vs. Notre Dame picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: