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Pittsburgh vs. Notre Dame prediction: Notre Dame favored to win women's college basketball matchup [12/29/2025]

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Written by Ryan Leaver

Get Pittsburgh vs Notre Dame predictions for college basketball Monday.

Pittsburgh-Notre Dame Predictions and Game Preview.
Pittsburgh vs. Notre Dame women's college basketball prediction for Monday, December 29, 2025.

Notre Dame and Pittsburgh are scheduled to meet in the women's college basketball at Purcell Pavilion on Monday, with tipoff at 6:00 PM ET.

Based on updated simulation results, Dimers' new women's basketball model projects Notre Dame as the most likely winner of the Pittsburgh vs. Notre Dame game.

This article offers an expanded analysis of Monday's matchup, including best bets and picks.

Pittsburgh vs. Notre Dame prediction: Who will win?

Using innovative machine learning and data analysis, we have simulated the result of Monday's women's basketball matchup between Pittsburgh and Notre Dame 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model gives Notre Dame a 99% chance of defeating Pittsburgh.

According to our model, the over/under total of 138.5 points has a 55% chance of staying under.

 

Pittsburgh vs. Notre Dame odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type Pittsburgh Notre Dame
Spread +43.5 (-108) -43.5 (-110)
Total o138.5 (-110) u138.5 (-110)

All odds are correct at the time of publication and are subject to change.

Pittsburgh vs. Notre Dame picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Pittsburgh +43.5 -108
Total Under 138.5 -110

According to our women's college basketball best bets, the top play to make on this game is Pittsburgh +43.5.

 

Pittsburgh vs. Notre Dame game-day updates and essential details

Monday's women's basketball matchup between Notre Dame and Pittsburgh at Purcell Pavilion is scheduled to commence at 6:00 PM ET.

  • Who: Pittsburgh vs. Notre Dame
  • Date: Monday, December 29, 2025
  • Time: 6:00 PM ET/3:00PM PT
  • Venue: Purcell Pavilion

Conclusion

We predict Notre Dame, with a 99% win probability, will likely beat Pittsburgh on Monday.

AI and automation have enhanced this article to quickly deliver accurate Pittsburgh vs. Notre Dame insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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