Steelers vs. Chargers prediction: Chargers favored to win SNF Week 10, 2025

The Los Angeles Chargers and Pittsburgh Steelers are scheduled to meet in Week 10 of the NFL season at SoFi Stadium on Sunday, with kickoff at 8:20PM ET.

Based on updated simulations, Dimers' proven NFL model predicts the Chargers as the most likely winner of the Steelers vs. Chargers game.

This article offers an expanded analysis of this week's matchup, including touchdown scorer projections, best bets and player prop picks.

Steelers vs. Chargers prediction: Who will win, cover the spread?

Since our Steelers-Chargers predictions earlier in the week, we have simulated the outcome of Sunday's NFL matchup between the Steelers and Chargers 10,000 times as part of our NFL predictions coverage.

Our leading predictive model currently gives the Chargers a 60% chance of beating the Steelers in Week 10 of the NFL season. Our predicted final score has the Chargers winning 23-21.

According to our model, the bookmakers have got it right, and the Steelers and Chargers each have a 50% chance of covering the spread, while the over/under total of 45.5 points has a 53% chance of staying under.

To see win probabilities for every matchup this week, check out our expert NFL Week 10 straight up picks.

Steelers vs. Chargers odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type	Steelers	Chargers
Spread	+2.5 (-102)	-2.5 (-120)
Moneyline	+136	-150
Total	o45.5 (-105)	u45.5 (-115)

All odds are correct at the time of publication and are subject to change.

Steelers vs. Chargers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Steelers +2.5	-102
Moneyline	Chargers	-150
Total	Under 45.5	-115

According to our NFL best bets, the top play to make on this game is Chargers to win.

Steelers vs. Chargers TD scorers

Who will score a touchdown in Steelers vs. Chargers?

According to our list of touchdown scorer predictions for Week 10, Jaylen Warren is most likely to score an anytime TD in Steelers vs. Chargers.

Our projections give Warren a 44.0% chance of getting in for six at SoFi Stadium, while the running back is a 9.8% chance of scoring the first touchdown the game.

Anytime touchdown scorer predictions

Pittsburgh Steelers

Player	Anytime TD Probability
Jaylen Warren (RB)	44.0%
DK Metcalf (WR)	35.8%
Jonnu Smith (TE)	25.0%
Kenneth Gainwell (RB)	24.8%
Calvin Austin (WR)	24.4%

Los Angeles Chargers

Player	Anytime TD Probability
Kimani Vidal (RB)	43.0%
Keenan Allen (WR)	34.7%
Quentin Johnston (WR)	32.0%
Ladd McConkey (WR)	31.8%
Oronde Gadsden (TE)	29.0%

First touchdown scorer predictions

Pittsburgh Steelers

Player	First TD Probability
Jaylen Warren (RB)	9.8%
DK Metcalf (WR)	7.5%
Jonnu Smith (TE)	4.9%
Kenneth Gainwell (RB)	4.8%
Calvin Austin (WR)	4.8%

Los Angeles Chargers

Player	First TD Probability
Kimani Vidal (RB)	10.3%
Keenan Allen (WR)	7.8%
Quentin Johnston (WR)	7.1%
Ladd McConkey (WR)	7.0%
Oronde Gadsden (TE)	6.3%

Steelers vs Chargers player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Steelers and Chargers. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 10 games.

Quarterbacks

Of the starting quarterbacks, the Steelers' Aaron Rodgers is projected for 225 passing yards, while the Chargers' Justin Herbert is expected to throw for a whopping 267 yards.

Player	Proj. Pass Yards
Aaron Rodgers (PIT)	225
Justin Herbert (LAC)	267

Steelers rushing

Player	Proj. Rush Yards
Jaylen Warren	64
Kenneth Gainwell	23
Aaron Rodgers	5

Chargers rushing

Player	Proj. Rush Yards
Kimani Vidal	54
Justin Herbert	24
Jaret Patterson	22

Steelers receiving

Player	Proj. Rec. Yards
DK Metcalf	55
Calvin Austin	39
Jonnu Smith	29
Pat Freiermuth	27
Jaylen Warren	20

Chargers receiving

Player	Proj. Rec. Yards
Ladd McConkey	68
Oronde Gadsden	54
Quentin Johnston	49
Keenan Allen	49
Tre' Harris	18

Steelers vs. Chargers game-day updates and essential details

The NFL Week 10 game between the Chargers and Steelers at SoFi Stadium is scheduled to begin at 8:20PM ET.

• Who: Pittsburgh Steelers vs. Los Angeles Chargers
• Date: Sunday, November 9, 2025
• Time: 8:20PM ET/5:20PM PT
• Venue: SoFi Stadium

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Conclusion

We predict the Chargers, with a 60% win probability, will likely beat the Steelers in Week 10 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Steelers vs. Chargers insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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