Pittsburgh Steelers vs. Detroit Lions updated prediction featuring Kenneth Gainwell, Jahmyr Gibbs [Week 16, 2025]

Dimers' latest NFL predictions are live for Detroit Lions vs. Pittsburgh Steelers in Week 16, with our model giving the Lions a 70% of winning.

As Sunday approaches, both teams have updated their injury reports. A few lineup decisions are still up in the air, and those could shape how each side approaches this cross-conference meeting.

Since our early Lions-Steelers predictions, we’ve updated the win probabilities, score projections, and TD odds for Kenneth Gainwell, Jahmyr Gibbs, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—head to our Steelers vs. Lions page.

What's changed? Pittsburgh vs. Detroit updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Steelers vs. Lions matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Steelers 30%, Lions 70%
• Predicted Final Score: Steelers 22-28 Lions
• Spread: Steelers (+7) 53%, Lions (-7) 47%
• Total Points (52.5): Over 47%, Under 53%

As of December 18, 2025, these Steelers-Lions numbers reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 16 highlight the top candidates to find the end zone in Steelers-Lions on Sunday:

Pittsburgh Steelers

• Kenneth Gainwell: 42.3% probability
• Jaylen Warren: 37.9% probability
• DK Metcalf: 35.7% probability

Detroit Lions

• Jahmyr Gibbs: 65.5% probability
• Amon-Ra St. Brown: 49.0% probability
• David Montgomery: 41.7% probability

Steelers vs. Lions latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Steelers +7 (-105), Lions -7 (-110)
• Moneyline: Steelers +280, Lions -325
• Total: Over/Under 52.5 (-105/-115)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Steelers vs. Lions Week 16 details

The NFL Week 16 action between the Lions and Steelers at Ford Field is scheduled for December 21, 2025.

• Who: Pittsburgh Steelers vs. Detroit Lions
• Date: Sunday, December 21, 2025
• Time: 4:25 PM ET/1:25PM PT
• Venue: Ford Field

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Conclusion

We predict the Lions, with a 70% win probability, will likely beat the Steelers in Week 16 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Steelers vs. Lions game, with human oversight maintaining high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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