Loading...

Steelers vs. Lions prediction: Detroit favored to win in NFL Week 16 [2025]

profile-img
Written by Jason Bevilacqua

Get Pittsburgh Steelers vs Detroit Lions predictions for NFL Sunday.

Pittsburgh Steelers-Detroit Lions Predictions and Game Preview.
Pittsburgh Steelers vs. Detroit Lions NFL prediction for Sunday, December 21, 2025.

The Detroit Lions will square off with the Pittsburgh Steelers in NFL Week 16 action at Ford Field on Sunday, starting at 4:25 PM ET.

Based on updated simulations, Dimers' proven NFL model predicts the Lions as the most likely winner of the Steelers vs. Lions game.

This article offers further insights into Sunday's matchup, including projected touchdown scorers, best bets and player prop picks.

Steelers vs. Lions prediction: Who will win and cover?

Since our Steelers-Lions predictions earlier in the week, we have simulated the outcome of Sunday's NFL game between the Steelers and Lions 10,000 times as part of our NFL predictions coverage.

Our famous predictive model currently gives the Lions a 72% chance of defeating the Steelers in Week 16 of the NFL season. Our predicted final score has the Lions winning 29-22.

According to our model, the Steelers (+8) have a 54% chance of covering the spread, while the over/under total of 52.5 points has a 54% chance of staying under.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 16 straight up picks.

Steelers vs. Lions odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Steelers Lions
Spread +8 (-118) -8 (-105)
Moneyline +330 -400
Total o52.5 (-106) u52.5 (-110)

All odds are correct at the time of publication and are subject to change.

Steelers vs. Lions picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Steelers +8 -118
Moneyline Steelers +330
Total Under 52.5 -110

According to our NFL best bets, the top play to make on this game is Steelers to win.

 

Steelers vs. Lions TD scorers

Who will score a touchdown in Steelers vs. Lions?

According to our list of touchdown scorer predictions for Week 16, Jahmyr Gibbs is most likely to score an anytime touchdown in Steelers vs. Lions.

Our projections give Gibbs a 66.8% chance of scoring a TD at Ford Field, while the running back is a 17.4% chance of scoring the first touchdown the game.

Anytime touchdown scorer predictions

Pittsburgh Steelers

Player Anytime TD Probability
Kenneth Gainwell (RB) 42.8%
DK Metcalf (WR) 36.6%
Jaylen Warren (RB) 35.6%
Pat Freiermuth (TE) 19.2%
Darnell Washington (TE) 17.3%

Detroit Lions

Player Anytime TD Probability
Jahmyr Gibbs (RB) 66.8%
Amon-Ra St. Brown (WR) 51.0%
David Montgomery (RB) 42.4%
Jameson Williams (WR) 37.9%
Isaac TeSlaa (WR) 16.8%

First touchdown scorer predictions

Pittsburgh Steelers

Player First TD Probability
Kenneth Gainwell (RB) 8.9%
DK Metcalf (WR) 7.2%
Jaylen Warren (RB) 7.0%
Pat Freiermuth (TE) 3.4%
Darnell Washington (TE) 3.0%

Detroit Lions

Player First TD Probability
Jahmyr Gibbs (RB) 17.4%
Amon-Ra St. Brown (WR) 11.2%
David Montgomery (RB) 8.7%
Jameson Williams (WR) 7.5%
Isaac TeSlaa (WR) 2.9%

Steelers vs Lions player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Steelers and Lions. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 16 games.

Quarterbacks

Of the starting quarterbacks, the Steelers' Aaron Rodgers is projected for 233 passing yards, while the Lions' Jared Goff is expected to throw for a whopping 264 yards.

Player Proj. Pass Yards
Aaron Rodgers (PIT) 233
Jared Goff (DET) 264

Steelers rushing

Player Proj. Rush Yards
Jaylen Warren 45
Kenneth Gainwell 34
Aaron Rodgers 4

Lions rushing

Player Proj. Rush Yards
Jahmyr Gibbs 77
David Montgomery 37
Sione Vaki 4

Steelers receiving

Player Proj. Rec. Yards
DK Metcalf 66
Kenneth Gainwell 30
Darnell Washington 28
Pat Freiermuth 24
Marquez Valdes-Scantling 19

Lions receiving

Player Proj. Rec. Yards
Amon-Ra St. Brown 91
Jameson Williams 72
Jahmyr Gibbs 43
Isaac TeSlaa 17
Kalif Raymond 14

Steelers vs. Lions game-day updates and essential details

The NFL Week 16 game between the Lions and Steelers at Ford Field is scheduled to begin at 4:25 PM ET.

NFL Week 16 betting promos and codes

Make the most of Dimers' Steelers vs. Lions predictions by exploring the two exciting offers below.

DraftKings Sportsbook

Sign up for DraftKings Sportsbook! Bet $5, get $200 in bonus bets instantly plus over $200 off NFL Sunday Ticket.


Bet365 Sportsbook

Join Bet365 Sportsbook! Bet $5, get $200 in bonus bets win or lose.


Conclusion

We predict the Lions, with a 72% win probability, will likely beat the Steelers in Week 16 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Steelers vs. Lions insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

profile-img
Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

Advertiser disclosure

Related Articles

More Articles
Loading...
...
Read Article
...
Read Article
...
Read Article

Best Sportsbook Promotions

Why Join Multiple Sportsbooks?
Loading...