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76ers vs. Bucks prediction: Why Philadelphia is favored to win Friday's NBA matchup [12/5/2025]

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Written by Ryan Leaver

Get Philadelphia 76ers vs Milwaukee Bucks predictions for NBA Friday.

Philadelphia 76ers-Milwaukee Bucks Predictions and Game Preview.
Philadelphia 76ers vs. Milwaukee Bucks NBA prediction for Friday, December 5, 2025.

NBA action continues on Friday at 8:00PM ET as the Philadelphia 76ers lock horns with the Milwaukee Bucks at Fiserv Forum.

Based on the latest simulations and today’s injury updates, Dimers' proven NBA model predicts the 76ers as the most likely winner of the 76ers vs. Bucks game.

This prediction follows the latest NBA Injury Report, which suggests the Bucks lineup will feature stars like Kevin Porter, Ryan Rollins and Myles Turner, while the 76ers will look to Tyrese Maxey, Quentin Grimes and Paul George.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Sixers vs. Sixers prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Friday's NBA matchup between the 76ers and Bucks 10,000 times as part of our NBA predictions coverage.

Our leading predictive model currently gives the 76ers a 56% chance of beating the Bucks. Our predicted final score has the 76ers winning 111-109.

According to our model, the 76ers (-1.5) have a 52% chance of covering the spread, while the over/under total of 221.5 points has an equal 50-50 chance of hitting.

 

76ers vs. Bucks odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type 76ers Bucks
Spread -1.5 (-108) +1.5 (-110)
Moneyline -118 +100
Total o221.5 (-110) u221.5 (-105)

All odds are correct at the time of publication and are subject to change.

76ers vs. Bucks picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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