Newcastle Knights vs. Penrith Panthers prediction: Panthers favored to win Sunday's NRL Round 8 matchup [4/26/2026]
Get Newcastle Knights vs Penrith Panthers predictions for NRL Sunday.

The Newcastle Knights will square off with the favored Penrith Panthers in National Rugby League (NRL) action at McDonald Jones Stadium on Sunday, commencing at 12:00 AM ET.
Based on the latest simulations, Dimers' proven NRL model predicts the Panthers as the most likely winner of the Panthers vs. Knights game.
This article offers a closer look at Sunday's matchup, including best bets and picks.
Knights vs. Panthers prediction: Who will win Round 8 game?
Using trusted machine learning and data, we have simulated the outcome of Sunday's NRL matchup between the Panthers and Knights, forming part of our NRL predictions coverage.
Our famous predictive model gives the Panthers an 84% chance of beating the Knights.
According to our model, the bookmakers have got it right, and the Panthers and Knights each have a 50% chance of covering the spread, while the 53.5-point over/under has a 58% chance of staying under.
Panthers vs. Knights odds
We have researched the best NRL odds in America for this game, which are listed here:
| Bet Type | Panthers | Knights |
|---|---|---|
| H2H (Moneyline) | -500 | +340 |
| Line (Spread) | -14.5 (-135) | +14.5 (+105) |
| Total | o53.5 (-114) | u53.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Panthers vs. Knights picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Knights +14.5 | bet_rivers_in+105 |
| Moneyline | Panthers | bet_rivers_in-500 |
| Total | Under 53.5 | -112 |
According to our NRL best bets, the top play to make on this game is Under 53.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Knights vs. Panthers game-day updates and essential details
Sunday's Australian rugby league game between the Knights and Panthers at McDonald Jones Stadium is scheduled to begin at 12:00 AM ET.
- Who: Penrith Panthers vs. Newcastle Knights
- Date: Sunday, April 26, 2026
- Time: 12:00 AM ET/9:00PM PT
- Venue: McDonald Jones Stadium
The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.
Conclusion
We predict the Panthers, with an 84% win probability, will likely beat the Knights in Sunday's NRL matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



