Oklahoma vs. Mississippi State prediction: Why Mississippi State is favored to win men's college basketball matchup [1/7/2026]

Mississippi State will take on Oklahoma, in what is expected to be a close Men's College Basketball game, at Humphrey Coliseum on Wednesday, beginning at 7:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model gives Mississippi State a slight edge with a 54% win probability over Oklahoma.

This article offers a closer look at Wednesday's Oklahoma vs. Mississippi State matchup, including an expanded look at the predicted score, best bets and picks.

Oklahoma vs. Mississippi State prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between Oklahoma and Mississippi State 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Mississippi State a 54% chance of defeating Oklahoma. Our predicted final score has Mississippi State winning 80-78.

According to our model, Oklahoma (+1.5) has a 51% chance of covering the spread, while the over/under total of 158.5 points has a 51% chance of going over.

Oklahoma vs. Mississippi State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Oklahoma vs. Mississippi State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: