Oklahoma State vs. Iowa State prediction: Why Iowa State is favored to win men's college basketball matchup [1/10/2026]

Men's college basketball action continues on Saturday at 4:00 PM ET as Oklahoma State takes on Iowa State in men's college basketball action at James H. Hilton Coliseum.

Based on updated simulation results, Dimers' advanced college basketball model predicts Iowa State as the most likely winner of the Oklahoma State vs. Iowa State game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Oklahoma State vs. Iowa State prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Oklahoma State and Iowa State 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Iowa State a 96% chance of defeating Oklahoma State. Our predicted final score has Iowa State winning 89-67.

According to our model, Iowa State (-20.5) has a 54% chance of covering the spread, while the 165.5-point over/under has a 56% chance of staying under.

Oklahoma State vs. Iowa State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Oklahoma State vs. Iowa State picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: