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Ohio State vs. Purdue prediction: Why Ohio State is favored to win women's college basketball matchup [12/31/2025]
Get Ohio State vs Purdue predictions for college basketball Wednesday.

Purdue and Ohio State will lock horns in the women's college basketball at Mackey Arena on Wednesday, with tipoff at 12:30 PM ET.
Based on updated simulation results, Dimers' new women's basketball model predicts Ohio State as the most likely winner of the Ohio State vs. Purdue game.
This article offers further insights into Wednesday's matchup, including best bets and picks.
Ohio State vs. Purdue prediction: Who will win?
Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's women's basketball matchup between Ohio State and Purdue 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model currently gives Ohio State a 92% chance of beating Purdue.
According to our model, the over/under total of 152.5 points has a 60% chance of staying under.
Ohio State vs. Purdue odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Ohio State | Purdue |
|---|---|---|
| Spread | -10.5 (-110) | +10.5 (-110) |
| Moneyline | -625 | +520 |
| Total | o152.5 (-114) | u152.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Ohio State vs. Purdue picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Ohio State -10.5 | -110 |
| Moneyline | Ohio State | -625 |
| Total | Under 152.5 | -114 |
According to our best women's college basketball bets, the top play to make on this game is Ohio State -10.5 at the spread.
Ohio State vs. Purdue game-day updates and essential details
Wednesday's women's basketball matchup between Purdue and Ohio State at Mackey Arena is scheduled to commence at 12:30 PM ET.
- Who: Ohio State vs. Purdue
- Date: Wednesday, December 31, 2025
- Time: 12:30 PM ET/9:30AM PT
- Venue: Mackey Arena
Conclusion
We predict Ohio State, with a 92% win probability, will likely beat Purdue on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Ohio State vs. Purdue insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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