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Notre Dame vs. Syracuse prediction: Syracuse favored to win men's college basketball matchup [1/31/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Notre Dame vs Syracuse predictions for college basketball Saturday.
Syracuse will take on Notre Dame in men's college basketball action at JMA Wireless Dome on Saturday, commencing at 6:00 PM ET.
Based on the latest simulations, Dimers' advanced college basketball model predicts Syracuse as the most likely winner of the Notre Dame vs. Syracuse game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Notre Dame vs. Syracuse prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Notre Dame and Syracuse 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives Syracuse a 66% chance of defeating Notre Dame. Our predicted final score has Syracuse winning 76-71.
According to our model, Notre Dame (+5.5) has a 58% chance of covering the spread, while the over/under total of 147.5 points has a 52% chance of going over.
Notre Dame vs. Syracuse odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Notre Dame | Syracuse |
|---|---|---|
| Spread | +5.5 (-102) | -5.5 (-120) |
| Moneyline | +225 | -275 |
| Total | o147.5 (-110) | u147.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Notre Dame vs. Syracuse picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Notre Dame +5.5 | -102 |
| Moneyline | Notre Dame | +225 |
| Total | Over 147.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Notre Dame +5.5 at the spread.
Notre Dame vs. Syracuse game-day updates and essential details
Saturday's men's college basketball matchup between Syracuse and Notre Dame at JMA Wireless Dome is scheduled to commence at 6:00 PM ET.
- Who: Notre Dame vs. Syracuse
- Date: Saturday, January 31, 2026
- Time: 6:00 PM ET/3:00PM PT
- Venue: JMA Wireless Dome
Conclusion
We predict Syracuse, with a 66% win probability, will likely beat Notre Dame on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Notre Dame vs. Syracuse insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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