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Notre Dame vs. Ohio State prediction: Ohio State favored to win men's college basketball matchup [11/16/2025]

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Written by Jason Bevilacqua

Get Notre Dame vs Ohio State predictions for college basketball Sunday.

Notre Dame-Ohio State Predictions and Game Preview.
Notre Dame vs. Ohio State men's college basketball prediction for Sunday, November 16, 2025.

Ohio State will face Notre Dame in men's college basketball action at Value City Arena on Sunday, beginning at 12:30PM ET.

Based on updated simulations, Dimers' proven college basketball model projects Ohio State as the most likely winner of the Notre Dame vs. Ohio State game.

This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Notre Dame vs. Ohio State prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Sunday's NCAA basketball matchup between Notre Dame and Ohio State 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Ohio State a 78% chance of beating Notre Dame. Our predicted final score has Ohio State winning 83-74.

According to our model, Notre Dame (+9.5) has a 55% chance of covering the spread, while the 156.5-point over/under has a 52% chance of going over.

 

Notre Dame vs. Ohio State odds

We have researched the best Men's College Basketball odds in America for this game, which are listed here:

Bet Type Notre Dame Ohio State
Spread +9.5 (-102) -9.5 (-112)
Moneyline +390 -500
Total o156.5 (-105) u156.5 (-110)

All odds are correct at the time of publication and are subject to change.

Notre Dame vs. Ohio State picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Notre Dame +9.5 -102
Moneyline Notre Dame +390
Total Over 156.5 -105

According to our men's college basketball best bets, the top play to make on this game is Notre Dame +9.5 at the spread.

 

Notre Dame vs. Ohio State game-day updates and essential details

Sunday's men's college basketball game between Ohio State and Notre Dame at Value City Arena is scheduled to begin at 12:30PM ET.

  • Who: Notre Dame vs. Ohio State
  • Date: Sunday, November 16, 2025
  • Time: 12:30PM ET/9:30AM PT
  • Venue: Value City Arena

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Conclusion

We predict Ohio State, with a 78% win probability, will likely beat Notre Dame on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Notre Dame vs. Ohio State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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