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Northwestern vs. DePaul prediction: Northwestern favored to win women's college basketball matchup [11/17/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Northwestern vs DePaul predictions for college basketball Monday.
DePaul will square off with Northwestern, in what is expected to be a tight women's college basketball game, at Wintrust Arena on Monday, beginning at 12:00PM ET.
Based on the latest simulations, Dimers' new women's basketball model gives Northwestern a slight edge with a 53% win probability over DePaul.
This article offers an expanded analysis of Monday's Northwestern vs. DePaul matchup, including best bets and picks.
Northwestern vs. DePaul prediction: Who will win?
Using innovative machine learning and data, we have simulated the result of Monday's women's basketball matchup between Northwestern and DePaul 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model currently gives Northwestern a 53% chance of beating DePaul.
According to our model, the over/under total of 140.5 points has a 58% chance of going over.
Northwestern vs. DePaul odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Northwestern | DePaul |
|---|---|---|
| Spread | -1.5 (-110) | +1.5 (-110) |
| Total | o140.5 (-110) | u140.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Northwestern vs. DePaul picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | DePaul +1.5 | -110 |
| Total | Over 140.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is over 140.5 points.
Northwestern vs. DePaul game-day updates and essential details
Monday's women's basketball matchup between DePaul and Northwestern at Wintrust Arena is scheduled to commence at 12:00PM ET.
- Who: Northwestern vs. DePaul
- Date: Monday, November 17, 2025
- Time: 12:00PM ET/9:00AM PT
- Venue: Wintrust Arena
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Conclusion
We predict Northwestern, with a 53% win probability, will likely beat DePaul on Monday.
AI and automation have enhanced this article to quickly deliver accurate Northwestern vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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