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Northeastern vs. Duquesne prediction: Duquesne favored to win men's college basketball matchup [11/22/2025]

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Written by Dave Garofolo

Get Northeastern vs Duquesne predictions for college basketball Saturday.

Northeastern-Duquesne Predictions and Game Preview.
Northeastern vs. Duquesne men's college basketball prediction for Saturday, November 22, 2025.

Duquesne and Northeastern are scheduled to meet in men's college basketball action at LeBron James Arena on Saturday, starting at 4:00PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Duquesne as the most likely winner of the Northeastern vs. Duquesne game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Northeastern vs. Duquesne prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Northeastern and Duquesne 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Duquesne a 77% chance of beating Northeastern. Our predicted final score has Duquesne winning 76-69.

According to our model, Northeastern (+7.5) has a 51% chance of covering the spread, while the 146.5-point over/under has a 52% chance of staying under.

 

Northeastern vs. Duquesne odds

We have researched the best Men's College Basketball odds in America for this game, which are listed here:

Bet Type Northeastern Duquesne
Spread +7.5 (-102) -7.5 (-112)
Moneyline +300 -350
Total o146.5 (-114) u146.5 (-105)

All odds are correct at the time of publication and are subject to change.

Northeastern vs. Duquesne picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Northeastern +7.5 -102
Moneyline Duquesne -350
Total Under 146.5 -105

According to our men's college basketball best bets, the top play to make on this game is Under 146.5 total points.

 

Northeastern vs. Duquesne game-day updates and essential details

Saturday's men's college basketball matchup between Duquesne and Northeastern at LeBron James Arena is scheduled to begin at 4:00PM ET.

  • Who: Northeastern vs. Duquesne
  • Date: Saturday, November 22, 2025
  • Time: 4:00PM ET/1:00PM PT
  • Venue: LeBron James Arena

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Conclusion

We predict Duquesne, with a 77% win probability, will likely beat Northeastern on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Northeastern vs. Duquesne insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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