Nicholls State vs. Texas Rio Grande Valley prediction: Why Texas Rio Grande Valley is favored to win men's college basketball matchup [12/31/2025]

Texas Rio Grande Valley will face Nicholls State in men's college basketball action at UTRGV Fieldhouse on Wednesday, commencing at 5:30 PM ET.

Based on updated simulation results, Dimers' proven college basketball model projects Texas Rio Grande Valley as the most likely winner of the Nicholls State vs. Texas Rio Grande Valley game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Nicholls State vs. Texas Rio Grande Valley prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between Nicholls State and Texas Rio Grande Valley 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Texas Rio Grande Valley a 62% chance of beating Nicholls State. Our predicted final score has Texas Rio Grande Valley winning 75-72.

According to our model, Nicholls State (+3.5) has a 51% chance of covering the spread, while the 146.5-point over/under has a 53% chance of going over.

Nicholls State vs. Texas Rio Grande Valley odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Nicholls State vs. Texas Rio Grande Valley picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: