Nicholls State vs. Kentucky prediction: Kentucky favored to win men's college basketball matchup [11/4/2025]

Kentucky will square off with Nicholls State in men's college basketball action at Rupp Arena on Tuesday, starting at 7:00PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts the Kentucky as the most likely winner of the Nicholls State vs. Kentucky game.

This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Nicholls State vs. Kentucky prediction: Who will win, cover the spread?

Using trusted machine learning and data, we have simulated the result of Tuesday's NCAA basketball game between Nicholls State and Kentucky 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Kentucky a 98% chance of beating Nicholls State. Our predicted final score has Kentucky winning 90-63.

According to our model, Nicholls State (+30.5) has a 55% chance of covering the spread, while the over/under total of 153.5 points has a 52% chance of going over.

Nicholls State vs. Kentucky odds

We have sourced the best college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Nicholls State vs. Kentucky picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is Nicholls State +30.5 at the spread.

Nicholls State vs. Kentucky game-day updates and essential details

Tuesday's men's college basketball game between Kentucky and Nicholls State at Rupp Arena is scheduled to start at 7:00PM ET.

• Who: Nicholls State vs. Kentucky
• Date: Tuesday, November 4, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Rupp Arena

Conclusion

We predict Kentucky, with a 98% win probability, will likely beat Nicholls State on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Nicholls State vs. Kentucky insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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