Niagara vs. Canisius prediction: Why Canisius is favored to win men's college basketball matchup [1/14/2026]

Canisius will face Niagara in men's college basketball action at Koessler Athletic Center on Wednesday, beginning at 7:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Canisius as the most likely winner of the Niagara vs. Canisius game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Niagara vs. Canisius prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between Niagara and Canisius 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Canisius a 57% chance of defeating Niagara. Our predicted final score has Canisius winning 67-66.

According to our model, Niagara (+2.5) has a 53% chance of covering the spread, while the over/under total of 128.5 points has a 54% chance of going over.

Niagara vs. Canisius odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Niagara vs. Canisius picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: