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Yankees vs. Reds Prediction: Yankees Predicted to Win Wednesday's MLB Matchup [6/25/2025]

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Written by Dave Garofolo

Our expert prediction for Wednesday's New York Yankees vs Cincinnati Reds matchup.

New York Yankees-Cincinnati Reds Predictions and Game Preview.
Great American Ball Park sets the stage for the MLB matchup between the New York Yankees and Cincinnati Reds this Wednesday.

The Cincinnati Reds will face the favored New York Yankees in MLB action at Great American Ball Park on Wednesday, commencing at 7:10PM ET.

The Reds will send Brady Singer (7-5, 4.13 ERA) to the mound, while the Yankees are going with Max Fried (9-2, 2.05 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Yankees as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Yankees-Reds game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Yankees' chance of winning at 64%, with the Reds at 36%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Yankees vs. Reds predictions page.

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Reds vs. Yankees Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's MLB matchup between the Yankees and Reds 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Yankees a 64% chance of defeating the Reds.

According to our model, the Yankees (-1.5) have a 52% chance of covering the run line, while the over/under total of 9 runs has a 52% chance of staying under.

Pre-Game Probabilities
Last Updated: 11:28PM, Jun 25
Moneyline
Over / Under
Run Line
Yankees
Win %
59%
41%
Get the best bets with Dimers Pro
See Matchup
Reds
Yankees NYY
Win %
59%
41%
See Matchup
Reds CIN
Max Fried 9-2, 2.05 ERA
Brady Singer 7-5, 4.13 ERA
Get the best bets with Dimers Pro

Yankees vs. Reds Odds [6/25/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Yankees Reds
Run Line -1.5 (-131) +1.5 (+115)
Moneyline -210 +176
Total o9 (-118) u9 (-102)

All odds are correct at the time of publication and are subject to change.

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Yankees vs. Reds Picks and Best Bets

Our model's strongest edge in today's Yankees vs. Reds matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Yankees vs. Reds Game-Day Updates and Essential Details

Wednesday's MLB game between the Reds and Yankees at Great American Ball Park is scheduled to start at 7:10PM ET.

Dimers.com's full preview of Wednesday's Yankees vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any Yankees vs. Reds picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Yankees, with a 64% win probability, will likely beat the Reds on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest projections for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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