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Jets vs. Saints prediction: New Orleans favored to win in NFL Week 16 [2025]

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Written by Mac Douglass

Get New York Jets vs New Orleans Saints predictions for NFL Sunday.

New York Jets-New Orleans Saints Predictions and Game Preview.
New York Jets vs. New Orleans Saints NFL prediction for Sunday, December 21, 2025.

The New Orleans Saints and New York Jets will meet in Week 16 of the NFL season at Caesars Superdome on Sunday, starting at 1:00 PM ET.

Based on the latest simulations, Dimers' proven NFL model projects the Saints as the most likely winner of the Jets vs. Saints game.

This article offers a closer look at this week's matchup, including projected touchdown scorers, best bets and player prop picks.

Jets vs. Saints prediction: Who will win and cover?

Since our Jets-Saints predictions earlier in the week, we have simulated the result of Sunday's NFL matchup between the Jets and Saints 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the Saints a 74% chance of defeating the Jets in Week 16 of the NFL season. Our predicted final score has the Saints winning 22-17.

According to our model, the Jets (+6.5) have a 57% chance of covering the spread, while the over/under total of 40 points has a 53% chance of going over.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 16 straight up picks.

Jets vs. Saints odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type Jets Saints
Spread +6.5 (-105) -6.5 (-115)
Moneyline +260 -285
Total o40 (-110) u40 (-110)

All odds are correct at the time of publication and are subject to change.

Jets vs. Saints picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Jets +6.5 -105
Moneyline Saints -285
Total Over 40 -110

According to our NFL best bets, the top play to make on this game is Jets +6.5 at the spread.

 

Jets vs. Saints TD scorers

Who will score a touchdown in Jets vs. Saints?

According to our list of touchdown scorer predictions for Week 16, Audric Estime is most likely to score an anytime TD in Jets vs. Saints.

Our projections give Estime a 43.4% chance of scoring a TD at Caesars Superdome, while the running back is an 11.9% chance of scoring the first touchdown the game.

Anytime touchdown scorer predictions

New York Jets

Player Anytime TD Probability
Breece Hall (RB) 31.4%
Adonai Mitchell (WR) 27.9%
John Metchie (WR) 25.7%
Isaiah Davis (RB) 20.9%
Isaiah Williams (WR) 18.6%

New Orleans Saints

Player Anytime TD Probability
Audric Estime (RB) 43.4%
Chris Olave (WR) 32.7%
Tyler Shough (QB) 32.2%
Evan Hull (RB) 32.0%
Juwan Johnson (TE) 26.4%

First touchdown scorer predictions

New York Jets

Player First TD Probability
Breece Hall (RB) 7.9%
Adonai Mitchell (WR) 6.8%
John Metchie (WR) 6.2%
Isaiah Davis (RB) 4.9%
Isaiah Williams (WR) 4.3%

New Orleans Saints

Player First TD Probability
Audric Estime (RB) 11.9%
Chris Olave (WR) 8.2%
Tyler Shough (QB) 8.1%
Evan Hull (RB) 8.0%
Juwan Johnson (TE) 6.4%

Jets vs Saints player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Jets and Saints. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 16 games.

Quarterbacks

Of the starting quarterbacks, the Jets' Brady Cook is projected to have a quiet game with 172 passing yards, while the Saints' Tyler Shough is expected to throw for 222 yards.

Player Proj. Pass Yards
Brady Cook (NYJ) 172
Tyler Shough (NO) 222

Jets rushing

Player Proj. Rush Yards
Breece Hall 67
Isaiah Davis 27
Brady Cook 19

Saints rushing

Player Proj. Rush Yards
Audric Estime 43
Evan Hull 29
Tyler Shough 25

Jets receiving

Player Proj. Rec. Yards
Adonai Mitchell 47
John Metchie 36
Isaiah Williams 26
Jeremy Ruckert 22
Breece Hall 17

Saints receiving

Player Proj. Rec. Yards
Chris Olave 70
Juwan Johnson 42
Mason Tipton 29
Kevin Austin 26
Audric Estime 16

Jets vs. Saints game-day updates and essential details

The NFL Week 16 game between the Saints and Jets at Caesars Superdome is scheduled to start at 1:00 PM ET.

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Conclusion

We predict the Saints, with a 74% win probability, will likely beat the Jets in Week 16 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Jets vs. Saints insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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