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Jets vs. Saints prediction: New Orleans favored to win in NFL Week 16 [2025]

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Written by Mac Douglass

Get New York Jets vs New Orleans Saints predictions for NFL Sunday.

New York Jets-New Orleans Saints Predictions and Game Preview.
New York Jets vs. New Orleans Saints NFL prediction for Sunday, December 21, 2025.

The New Orleans Saints will take on the New York Jets in NFL Week 16 action at Caesars Superdome on Sunday, commencing at 1:00 PM ET.

Based on updated simulations, Dimers' advanced NFL model predicts the Saints as the most likely winner of the Jets vs. Saints game.

This article offers a closer look at this week's matchup, including projected touchdown scorers, best bets and player prop picks.

Jets vs. Saints prediction: Who will win and cover?

Since our Jets-Saints predictions earlier in the week, we have simulated the result of Sunday's NFL matchup between the Jets and Saints 10,000 times as part of our NFL predictions coverage.

Our independent predictive model currently gives the Saints a 74% chance of beating the Jets in Week 16 of the NFL season. Our predicted final score has the Saints winning 23-17.

According to our model, the Jets (+6.5) have a 57% chance of covering the spread, while the over/under total of 40.5 points has an equal 50-50 chance of hitting.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 16 straight up picks.

Jets vs. Saints odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Jets Saints
Spread +6.5 (-110) -6.5 (-106)
Moneyline +240 -285
Total o40.5 (-105) u40.5 (-110)

All odds are correct at the time of publication and are subject to change.

Jets vs. Saints picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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