New Orleans Saints vs. Tennessee Titans updated prediction featuring Audric Estime, Tyjae Spears [Week 17, 2025]

Dimers' latest NFL predictions are live for Tennessee Titans vs. New Orleans Saints in Week 17, with our model giving the Saints a 59% of winning.

As Sunday approaches, both teams have updated their injury reports. Some lineup calls are still undecided, and those could shape how each side approaches this cross-conference meeting.

Since our early Titans-Saints predictions, we’ve updated the win probabilities, score projections, and TD odds for Audric Estime, Tyjae Spears, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—head to our Saints vs. Titans page.

What's changed? New Orleans vs. Tennessee updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Saints vs. Titans matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Saints 59%, Titans 41%
• Predicted Final Score: Saints 20-18 Titans
• Spread: Saints (-2.5) 50%, Titans (+2.5) 50%
• Total Points (39.5): Over 50%, Under 50%

As of December 25, 2025, these Saints-Titans figures reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 17 highlight the top candidates to find the end zone in Saints-Titans on Sunday:

New Orleans Saints

• Audric Estime: 37.3% probability
• Taysom Hill: 35.9% probability
• Chris Olave: 35.1% probability

Tennessee Titans

• Tyjae Spears: 29.7% probability
• Tony Pollard: 28.4% probability
• Chimere Dike: 26.1% probability

Saints vs. Titans latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Saints -2.5 (-114), Titans +2.5 (-105)
• Moneyline: Saints -148, Titans +126
• Total: Over/Under 39.5 (-106/-110)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Saints vs. Titans Week 17 details

The NFL Week 17 matchup between the Titans and Saints at Nissan Stadium is scheduled for December 28, 2025.

• Who: New Orleans Saints vs. Tennessee Titans
• Date: Sunday, December 28, 2025
• Time: 1:00 PM ET/10:00AM PT
• Venue: Nissan Stadium

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Conclusion

We predict the Saints, with a 59% win probability, will likely beat the Titans in Week 17 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Saints vs. Titans game, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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