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Saints vs. Titans prediction: Why New Orleans is favored to win in NFL Week 17 [2025]

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Written by Dave Garofolo

Get New Orleans Saints vs Tennessee Titans predictions for NFL Sunday.

New Orleans Saints-Tennessee Titans Predictions and Game Preview.
New Orleans Saints vs. Tennessee Titans NFL prediction for Sunday, December 28, 2025.

The Tennessee Titans and New Orleans Saints will meet in Week 17 of the NFL season at Nissan Stadium on Sunday, starting at 1:00 PM ET.

Based on the latest simulations, Dimers' proven NFL model projects the Saints as the most likely winner of the Saints vs. Titans game.

This article offers further insights into this week's matchup, including projected touchdown scorers, best bets and player prop picks.

Saints vs. Titans prediction: Who will win and cover?

Since our Saints-Titans predictions earlier in the week, we have simulated the outcome of Sunday's NFL matchup between the Saints and Titans 10,000 times as part of our NFL predictions coverage.

Our leading predictive model gives the Saints a 60% chance of beating the Titans in Week 17 of the NFL season. Our predicted final score has the Saints winning 19-17.

According to our model, the Saints (-1.5) have a 53% chance of covering the spread, while the over/under total of 38.5 points has a 54% chance of staying under.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 17 straight up picks.

Saints vs. Titans odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type Saints Titans
Spread -1.5 (+102) +1.5 (-115)
Moneyline -110 -102
Total o38.5 (-114) u38.5 (-105)

All odds are correct at the time of publication and are subject to change.

Saints vs. Titans picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Saints -1.5 +102
Moneyline Saints -110
Total Under 38.5 -105

According to our NFL best bets, the top play to make on this game is Saints to win.

 

Saints vs. Titans TD scorers

Who will score a touchdown in Saints vs. Titans?

According to our list of touchdown scorer predictions for today, Taysom Hill is most likely to score an anytime touchdown in Saints vs. Titans.

Our projections give Hill a 39.6% chance of scoring a TD at Nissan Stadium, while the tight end is a 10.4% chance of scoring the first touchdown the game.

Anytime touchdown scorer predictions

New Orleans Saints

Player Anytime TD Probability
Taysom Hill (TE) 39.6%
Chris Olave (WR) 36.2%
Evan Hull (RB) 27.3%
Juwan Johnson (TE) 23.9%
Audric Estime (RB) 23.8%

Tennessee Titans

Player Anytime TD Probability
Tyjae Spears (RB) 29.9%
Chimere Dike (WR) 27.7%
Tony Pollard (RB) 23.9%
Elic Ayomanor (WR) 22.6%
Van Jefferson (WR) 16.5%

First touchdown scorer predictions

New Orleans Saints

Player First TD Probability
Taysom Hill (TE) 10.4%
Chris Olave (WR) 9.3%
Evan Hull (RB) 6.6%
Juwan Johnson (TE) 5.6%
Audric Estime (RB) 5.6%

Tennessee Titans

Player First TD Probability
Tyjae Spears (RB) 8.8%
Chimere Dike (WR) 8.1%
Tony Pollard (RB) 6.8%
Elic Ayomanor (WR) 6.4%
Van Jefferson (WR) 4.5%

Saints vs Titans player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Saints and Titans. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 17 games.

Quarterbacks

Of the starting quarterbacks, the Saints' Tyler Shough is projected for 233 passing yards, while the Titans' Cam Ward is expected to throw for 190 yards.

Player Proj. Pass Yards
Tyler Shough (NO) 233
Cam Ward (TEN) 190

Saints rushing

Player Proj. Rush Yards
Audric Estime 36
Taysom Hill 22
Evan Hull 20

Titans rushing

Player Proj. Rush Yards
Tony Pollard 64
Tyjae Spears 29
Cam Ward 10

Saints receiving

Player Proj. Rec. Yards
Chris Olave 74
Juwan Johnson 47
Kevin Austin 30
Dante Pettis 18
Audric Estime 18

Titans receiving

Player Proj. Rec. Yards
Chimere Dike 35
Elic Ayomanor 31
Chig Okonkwo 28
Gunnar Helm 28
Van Jefferson 28

Saints vs. Titans game-day updates and essential details

The NFL Week 17 matchup between the Titans and Saints at Nissan Stadium is scheduled to start at 1:00 PM ET.

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Conclusion

We predict the Saints, with a 60% win probability, will likely beat the Titans in Week 17 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Saints vs. Titans insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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