Nevada vs. Santa Clara prediction: Santa Clara favored to win men's college basketball matchup [11/15/2025]

Men's college basketball action continues on Saturday at 7:00PM ET as Nevada takes on the favored Santa Clara in men's college basketball action at Leavey Center.

Based on updated simulation results, Dimers' advanced college basketball model predicts Santa Clara as the most likely winner of the Nevada vs. Santa Clara game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Nevada vs. Santa Clara prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Nevada and Santa Clara 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Santa Clara a 76% chance of defeating Nevada. Our predicted final score has Santa Clara winning 79-71.

According to our model, Santa Clara (-6.5) has a 55% chance of covering the spread, while the over/under total of 145.5 points has a 57% chance of going over.

Nevada vs. Santa Clara odds

We have sourced the best Men's College Basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Nevada vs. Santa Clara picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Over 145.5 total points.

Nevada vs. Santa Clara game-day updates and essential details

Saturday's men's college basketball matchup between Santa Clara and Nevada at Leavey Center is scheduled to begin at 7:00PM ET.

• Who: Nevada vs. Santa Clara
• Date: Saturday, November 15, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Leavey Center

Sports betting deal available for Saturday

To make the most of Saturday's exciting day of sports, headlined by college football Saturday games, check out details on the latest Bet365 bonus code "DIMERS" that grants you $200 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict Santa Clara, with a 76% win probability, will likely beat Nevada on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Nevada vs. Santa Clara insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.