Murray State vs. Southern Illinois prediction: Murray State favored to win men's college basketball matchup [2/6/2026]

Southern Illinois and Murray State will meet in men's college basketball action at Banterra Center on Friday, starting at 8:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model gives Murray State a slight edge with a 54% win probability over Southern Illinois.

This article offers an expanded analysis of Friday's Murray State vs. Southern Illinois matchup, including an expanded look at the predicted score, best bets and picks.

Murray State vs. Southern Illinois prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the outcome of Friday's NCAA basketball game between Murray State and Southern Illinois 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Murray State a 54% chance of defeating Southern Illinois. Our predicted final score has Murray State winning 79-78.

According to our model, Southern Illinois (+1.5) has a 51% chance of covering the spread, while the 157.5-point over/under has a 52% chance of staying under.

Murray State vs. Southern Illinois odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Murray State vs. Southern Illinois picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is Murray State to win.

Murray State vs. Southern Illinois game-day updates and essential details

Friday's men's college basketball matchup between Southern Illinois and Murray State at Banterra Center is scheduled to begin at 8:00 PM ET.

• Who: Murray State vs. Southern Illinois
• Date: Friday, February 6, 2026
• Time: 8:00 PM ET/5:00PM PT
• Venue: Banterra Center

Conclusion

We predict Murray State, with a 54% win probability, will likely beat Southern Illinois on Friday.

AI and automation have enhanced this article to quickly deliver accurate Murray State vs. Southern Illinois insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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